Sequence specific dihedral angle distribution: application in protein structure prediction & evaluation

نویسندگان

  • S. M. Minhaz Ud-Dean
  • Mahdi Muhammad Moosa
چکیده

Protein structure prediction and evaluation is one of the major fields of computational biology. Estimation of dihedral angle can provide information about the acceptability of both theoretically predicted and experimentally determined structures. Here we report on the sequence specific dihedral angle distribution of high resolution protein structures available in PDB and Sasichandran, a tool for sequence specific dihedral angle prediction and structure evaluation. This tool will allow evaluation of a protein structure in pdb format from the sequence specific distribution of Ramachandran angles. Additionally, it will allow retrieval of the most probable Ramachandran angles for a given sequence along with the sequence specific data.

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تاریخ انتشار 2009